Metaz products are FOR DERMATOLOGICAL USE ONLY, these are NOT FOR OPHTHALMIC USE. In cases of chronic toxicity, slow withdrawal of corticosteroids is advised. Treat electrolyte imbalance, if necessary. Acute hypercorticoid symptoms are virtually reversible. Appropriate symptomatic treatment is indicated. Excessive, prolonged use of topical corticosteroids can suppress pituitary-adrenal function resulting in secondary adrenal insufficiency. Nevertheless, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Drugs of this class should not be used on pregnant patients in large amounts or for prolonged periods of time. Since the safe use of Metaz products in pregnant women has not been established, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Chronic corticosteroid therapy may interfere with the growth and development of children. The use of topical corticosteroids in children should be limited to the least amount compatible with an effective therapeutic regimen. Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced hypothalamic-pituitary axis suppression and Cushing’s syndrome than mature patients because of a larger skin surface area to body weight ratio. Suitable precautions should be taken under these conditions or when long-term use is anticipated, particularly in infants and children. Systemic absorption of topical corticosteroids will be increased if extensive body surface areas are treated or if the occlusive technique is used. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection is controlled adequately.Īny of the side effects that have been reported following systemic use of corticosteroids, including adrenal suppression, may also occur with topical corticosteroids, especially in infants and children. In the presence of an infection, the use of an appropriate antifungal or antibacterial agent should be instituted. If irritation or sensitization develops with the use of Metaz products, treatment should be discontinued and appropriate therapy instituted. Metaz Cream and Ointment 0.1% are also contraindicated in fungal, tubercular skin infections or viral skin infections such as herpes simplex or zoster, facial rosacea, acne vulgaris & perioral dermatitis. Metaz Cream and Ointment 0.1% are contraindicated in patients who are sensitive to mometasone furoate, to other corticosteroids, or to any component of these preparations.
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